Puretech Health has been granted a patent for lymphatic system-directing lipid prodrugs, pharmaceutical compositions, and methods for improving bioavailability of therapeutic agents. The invention also includes methods for treating diseases by administering the lipid prodrug. GlobalData’s report on Puretech Health gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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Data Insights Puretech Health Plc - Company Profile

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According to GlobalData’s company profile on Puretech Health, Peptide pharmacophores was a key innovation area identified from patents. Puretech Health's grant share as of January 2024 was 24%. Grant share is based on the ratio of number of grants to total number of patents.

Lymphatic system-directing lipid prodrugs

Source: United States Patent and Trademark Office (USPTO). Credit: Puretech Health Plc

A recently granted patent (Publication Number: US11883497B2) discloses a compound of Formula X-b, with specific variations outlined in the claims. The compound includes features such as R1 and R2 being —C(O)R3, where each R3 is a saturated or unsaturated, unbranched C2-37 hydrocarbon chain. Additionally, the patent specifies that at least one instance of R4 is not hydrogen, with examples provided where one instance of R4 is C1-4 alkyl and the other is hydrogen, such as methyl.

Furthermore, the patent claims cover the use of the compound in pharmaceutical compositions, along with a pharmaceutically acceptable carrier, adjuvant, or vehicle. The therapeutic agents mentioned in the claims include testosterone, mycophenolic acid (MPA), buprenorphine, tetrahydrocannabinol (THC), cannabidiol, celecoxib, or dexamethasone. Specific combinations are highlighted, such as the compound with testosterone, THC, or cannabidiol. The claims also emphasize the possibility of R1 and R2 being —C(O)R3, providing a comprehensive overview of the compound's potential applications and variations within the pharmaceutical field.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies