Radius Health. has filed a patent for using PTHrP or analogues like abaloparatide to prevent bone fractures and increase bone mineral density in subjects. The method involves administering abaloparatide followed by alendronate to reduce the risk of non-vertebral bone fractures. GlobalData’s report on Radius Health gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Radius Health, Microneedles for transdermal drug delivery was a key innovation area identified from patents. Radius Health's grant share as of January 2024 was 33%. Grant share is based on the ratio of number of grants to total number of patents.
Treatment for reducing non-vertebral bone fractures
A recently filed patent (Publication Number: US20230381283A1) outlines a method for reducing the risk of non-vertebral bone fractures and improving bone mineral density (BMD) in individuals in need of such treatment. The method involves administering 80 µg of abaloparatide via subcutaneous injection for 18 months, followed by oral administration of alendronate at varying doses for an additional six months. The patent specifies that the subject may be a woman, particularly a postmenopausal woman with osteoporosis or high cortical porosity, and the non-vertebral bones targeted for fracture risk reduction include wrist and hip bones.
Furthermore, the patent claims that the method results in an increase in total hip BMD by 2% to 6.5% and an increase in femoral neck BMD by at least 4.5%. The treatment is tailored to individuals with normal BMD or a BMD T-score of at least about -1, indicating its potential efficacy in a wide range of patients. The combination of abaloparatide and alendronate is proposed as a promising approach to address bone health concerns, particularly in postmenopausal women with osteoporosis or high cortical porosity. The patent's detailed claims provide a clear outline of the method's parameters and expected outcomes, offering valuable insights into potential advancements in bone fracture prevention and BMD improvement.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
