RLS-0071 is under clinical development by ReAlta Life Sciences and currently in Phase I for Hypoxic-Ischemic Encephalopathy. According to GlobalData, Phase I drugs for Hypoxic-Ischemic Encephalopathy does not have sufficient historical data to build an indication benchmark PTSR for Phase I. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the RLS-0071 LoA Report. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

RLS-0071 overview

RLS-0071 (PIC1-01) is under development for the treatment of graft versus host disease (GvHD), neonatal hypoxic-ischemic encephalopathy (HIE), systemic lupus erythematosus (SLE), acute hemolysis (acute hemolytic transfusion reactions), infectious diseases caused by Pseudomonas aeruginosa, influenza virus infections, respiratory syncytial virus infections and severe asthma, acute lung injury due to COVID-19 Gardnerella vaginalis, Prevotella bivia and acute exacerbations of chronic obstructive pulmonary disease (AE-COPD. The drug candidate consists of a 15 amino acid peptide conjugated with PEG and acts by targeting the complement C1q. It is administered through intravenous route.
The therapeutic candidate was under development for the treatment of systemic lupus erythematosus (SLE), Staphylococcus aureus, Klebsiella pneumoniae, Neisseria meningitidis and Neisseria gonorrhoeae.

ReAlta Life Sciences overview

ReAlta Life Sciences is a clinical stage biotech company. The company discovers, develops, novel therapeutics with a dual targeting approach designed to rebalance complement and inflammatory processes through its PIC1 technology platform. Its first target is complemented pathway and second target is inhibiting innate inflammatory processes. The company’s product pipeline includes neurology, pulmonology, hematology for the treatment of hypoxic ischemic encephalopathy (HIE), acute lung injury and severe asthma, acute pulmonary exacerbations, chronic obstructive pulmonary disease (COPD), and platelet refractoriness. It also provides research and development services. ReAlta Life Sciences is headquartered in Norfolk, Virginia, the US.

For a complete picture of RLS-0071’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 February 2024

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.