RO-7297089 is under clinical development by Affimed and currently in Phase I for Relapsed Multiple Myeloma. According to GlobalData, Phase I drugs for Relapsed Multiple Myeloma have an 80% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how RO-7297089’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

RO-7297089 overview

RO-7297089 (AFM-26) is under development for the treatment of relapsed or refractory multiple myeloma. The therapeutic candidate is a NK-cell T and Ab which acts by targeting NK-cell via CD16A receptor and tumor specific B-cell maturation antigen (BCMA). The drug candidate is a bi-specific monoclonal antibody being developed based on Redirected Optimized Cell Killing (ROCK) platform. It is administered through the intravenous route.












Affimed overview

Affimed, formerly Affimed Therapeutics, a subsidiary of Affimed NV, discovers and develops immunotherapies to treat hematologic cancers and solid tumors. The company is investigating AFM13, an innate cell engager, for the treatment of Peripheral T cell lymphoma, transformed mycosis fungoides, CD30-positive T cell lymphoma and Hodgkin’s lymphoma; AFM24, against solid tumors; AFM-26, targeting B-cell maturation antigen to treat multiple myeloma. It generates multi-specific antibodies to kill tumor cells and treat cancers through its ROCK platform technology. The company works in partnership with Amphivena Therapeutics Inc, Merck & Co Inc, Genentech Inc, AbCheck SRO and other companies to advance its pipeline. Affimed is headquartered in Heidelberg, Baden-Wurttemberg, Germany

For a complete picture of RO-7297089’s drug-specific PTSR and LoA scores, buy the report here.

GlobalData

GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.