RVU-120 is under clinical development by Ryvu Therapeutics and currently in Phase II for Chronic Idiopathic Myelofibrosis (Primary Myelofibrosis). According to GlobalData, Phase II drugs for Chronic Idiopathic Myelofibrosis (Primary Myelofibrosis) does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the RVU-120 LoA Report. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

RVU-120 overview

RVU-120 is under development for the treatment of hematological tumors, triple negative breast cancer, myeloproliferative disorders, lymphomas including primary or secondary myelofibrosis, solid tumors, relapsed/refractory acute myeloid leukemia, diffuse large B-cell lymphoma, polycythemia vera, anemia and myelodysplastic syndrome. The drug candidate is administered through oral route. It acts by targeting Cyclin Dependent Kinase 19 and Cyclin Dependent Kinase 8.
It was also under development for the treatment of mantle cell lymphoma, colorectal cancer, acute lymphatic leukemia, breast cancer, Wilms’ tumors(nephroblastoma), congenital hypoblastic anemia, non-Hodgkin's lymphoma, myleoproliferatory disorder and prostate cancer.

Ryvu Therapeutics overview

Ryvu Therapeutics is a biopharmaceutical company that specializes in the discovery and development of novel small-molecule therapies in the area of oncology. The company is headquartered in Krakow, Lesser Poland, Poland.

For a complete picture of RVU-120’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.