GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

SB-11285 overview

SB-11285 is under development for the treatment of immuno-oncology diseases including solid tumors including malignant melanoma, recurrent head and neck cancer squamous cell carcinoma, renal cell carcinoma, hepatocellular carcinoma, Merkle cell carcinoma, urothelial cancer, non-small cell lung cancer, gastric carcinoma, ovarian carcinoma, endometrial, triple negative breast cancer, cervical cancer, colorectal carcinoma. The drug candidate is administered through oral, intravenous and intratumor routes and it is developed based on proprietary small molecule nucleic acid hybrid (SMNH) platform technology. The drug candidate targets STING (Stimulator of Interferon Gene) protein.

It was under development for the treatment of pancreatic cancer, bladder cancer, and lymphoma.

F-star Therapeutics overview

F-star Therapeutics, a subsidiary of invoX Pharma Ltd, is a clinical-stage biopharmaceutical company that develops novel, innovative tetravalent bispecific antibodies for cancer and serious illnesses. The company’s pipeline products include FS118, FS120, FS222 and SB 11285. Its pipeline candidates treat rescuing clinical practice improvement (CPI) treatment failures and improving outcomes in the clinical practice improvement (CPI) naive, improving outcomes in programmed cell death ligand 1 (PD-L1) low tumors, improving CPI and chemotherapy outcomes. F-star Therapeutics partners programs include multiple blood-brain barriers, multiple immuno-oncology, STING inhibitors and multiple next-generation bispecific antibodies. The company works in partnership with Denali Therapeutics Inc, Merck KGaA and Takeda Pharmaceutical Company Limited. It operates in the UK and the US. F-star Therapeutics is headquartered in Cambridge, England, the UK.

For a complete picture of SB-11285’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 20 February 2024

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GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.

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