Senaparib is under clinical development by IMPACT Therapeutics and currently in Phase II for Solid Tumor. According to GlobalData, Phase II drugs for Solid Tumor have a 10% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Senaparib’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Senaparib overview
Senaparib is under development for the treatment of solid tumours including small cell lung cancer, metastatic castration-resistant prostate cancer (mCRPC), ovarian cancer, fallopian tube cancer, epithelial ovarian cancer, peritoneal cancer, lung cancer and breast cancer. The drug candidate targets PARP (Poly(ADP-ribose) polymerase). The drug candidate was also under development for melanoma, prostate cancer and liver cancer. It is administered through oral route.
IMPACT Therapeutics overview
IMPACT Therapeutics (IMPACT) is a developer of therapeutics to treat cancer and other life-threatening diseases. The company provides products such as microtubule inhibitors, PARP-1 inhibitors, and Hedgehog pathway inhibitors for oncology. Its PARP-1 inhibitor is an oral bioavailability; and IMP04297 is an efficacious in several animal cancer models. The company also develops IMP3138, a small molecular microtubule inhibitor clinical candidate with advantages in vitro and in vivo over paclitaxel. It also operates oncology drug discovery and several anticancer drug development projects. IMPACT is headquartered in Nanjing, China.
For a complete picture of Senaparib’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
