The Serine/Threonine Protein Kinase Pim 2 pipeline drugs market research report outlays comprehensive information on the Serine/Threonine Protein Kinase Pim 2 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Serine/Threonine Protein Kinase Pim 2 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Immunology, and Gastrointestinal which include the indications Hematological Tumor, Post-Polycythemia Vera Myelofibrosis (PPV-MF), Psoriasis, Rheumatoid Arthritis, and Inflammatory Bowel Disease. It also reviews key players involved in Serine/Threonine Protein Kinase Pim 2 targeted therapeutics development with respective active and dormant or discontinued products.
The Serine/Threonine Protein Kinase Pim 2 pipeline targets constitutes close to eight molecules. Out of which, approximately eight molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase II, Phase I, and Preclinical stages are 1, 1, and 6 respectively.
Serine/Threonine Protein Kinase Pim 2 overview
Serine/threonine-protein kinase Pim-2 is an enzyme encoded by the PIM2. It is involved in cell survival and cell proliferation. It regulates cap-dependent protein translation in a mammalian target of rapamycin complex 1 (mTORC1)-independent manner and in parallel to the PI3K-Akt pathway. It mediates survival signaling through phosphorylation of BAD, which induces release of the anti-apoptotic protein Bcl-X (L)/BCL2L1. It promotes cell survival in response to a variety of proliferative signals via positive regulation of the I-kappa-B kinase/NF-kappa-B cascade.
For a complete picture of Serine/Threonine Protein Kinase Pim 2’s drug pipeline, buy the report here.
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