SGN-1 is under clinical development by Guangzhou Huajin Pharmaceutical Technology and currently in Phase II for Head And Neck Squamous Cell Carcinoma (HNSC). According to GlobalData, Phase II drugs for Head And Neck Squamous Cell Carcinoma (HNSC) have a 26% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how SGN-1’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

SGN-1 overview

SGN-1 is under development for the treatment of liver cancer, head and neck cancer squamous cell carcinoma, non-hodgkin lymphoma, hodgkin lymphoma, skin cancer, sarcoma, pancreatic cancer, prostate cancer, pseudomyxoma peritoneum (pseudomyxoma peritonei, PMP), squamous non-small cell carcinoma, cervical carcinoma, breast cancer, triple negative breast cancer, melanoma, head and neck cancer, ovarian cancer, small-cell lung cancer, bladder cancer, nasopharyngeal cancer and hepatocellular carcinoma. The drug candidate is administered by intratumoral and intravenous routes.It is a genetically modified strain of Salmonella enterica, serotype typhimurium that expresses L-Methioninase, It acts by targeting amino acid metabolism.

It was also under development for the treatment of osteosarcoma and penile cancer.

Guangzhou Huajin Pharmaceutical Technology overview

Guangzhou Huajin Pharmaceutical Technology is a biotechnology firm specializing in the development and production of innovative biological oncology drugs for the treatment of malignant tumors. The company is headquartered in Guangzhou, Guangdong, China.

For a complete picture of SGN-1’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

Data Insights


The gold standard of business intelligence.

Blending expert knowledge with cutting-edge technology, GlobalData’s unrivalled proprietary data will enable you to decode what’s happening in your market. You can make better informed decisions and gain a future-proof advantage over your competitors.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.