Sodium thiosulfate is under clinical development by Byondis and currently in Phase II for Drug Toxicity. According to GlobalData, Phase II drugs for Drug Toxicity have a 65% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how Sodium thiosulfate’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Sodium thiosulfate overview
Sodium thiosulfate is under development for the treatment of ocular toxicity in metastatic breast cancer patients treated with SYD985. It is administered by intraocular route in the form of drops.
Byondis overview
Byondis, discovers and develops innovative precision medicines for the treatment of auto-immune diseases including cancer. The company’s pipeline includes trastuzumab, SYD985, BYON3521, BYON4228 and BYON4413. Its pipeline candidates treat breast and gastric cancer and endometrial cancer. It is advancing its lead candidate: SYD985, a novel duocarmycin-based HER2-targeting antibody-drug conjugate (ADC), and a portfolio of preclinical and clinical programs with an aim to provide novel treatments for solid tumors that overexpress HER2, uterine serous carcinoma and auto-immune diseases. It harnesses its proprietary linker-drug (LD) technology to generate ADCs targeting treatment for different indications. The company works in collaboration with pharmaceutical companies including Amgen, Allergan and Macrogenics; academic institutions; and medical communities worldwide. Byondis is headquartered in Nijmegen, Gelderland, the Netherlands.
For a complete picture of Sodium thiosulfate’s drug-specific PTSR and LoA scores, buy the report here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.
