The Stearoyl CoA Desaturase pipeline drugs market research report outlays comprehensive information on the Stearoyl CoA Desaturase targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Stearoyl CoA Desaturase pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Gastrointestinal, Metabolic Disorders, and Central Nervous System which include the indications Colorectal Cancer, Triple-Negative Breast Cancer (TNBC), Metabolic Dysfunction-Associated Steatohepatitis (MASH), Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), Obesity, Diabetes, Lewy Body Dementia, and Parkinson’s Disease. It also reviews key players involved in Stearoyl CoA Desaturase targeted therapeutics development with respective active and dormant or discontinued products.
The Stearoyl CoA Desaturase pipeline targets constitutes close to 11 molecules. Out of which, approximately ten molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, Preclinical, and Discovery stages are 1, 1, 1, 6, and 1 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Stearoyl CoA Desaturase overview
Stearoyl-CoA desaturase 1 is a protein encoded by the SCD gene. Stearoyl-CoA desaturase-1 plays an important enzyme in fatty acid metabolism. Alteration in SCD1 expression changes the fatty acid profile of these lipids and produces diverse effects on cellular function. High SCD1 expression is correlated with metabolic diseases such as obesity and insulin resistance, whereas low levels are protective against these metabolic disturbances. SCD1 is also involved in the regulation of inflammation and stress in distinct cell types, including β-cells, adipocytes, macrophages, endothelial cells, and myocytes. Complete loss of SCD1 expression has been implicated in liver dysfunction and several inflammatory diseases such as dermatitis, atherosclerosis, and intestinal colitis.
For a complete picture of Stearoyl CoA Desaturase’s drug pipeline, buy the report here.
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