Sulopenem Etzadroxil is a small molecule commercialized by Iterum Therapeutics, with a leading Phase III program in Complicated Intra-Abdominal Infections. According to Globaldata, it is involved in 9 clinical trials, of which 7 were completed, and 2 are ongoing. GlobalData uses proprietary data and analytics to provide a complete picture of Sulopenem Etzadroxil’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for Sulopenem Etzadroxil is expected to reach an annual total of $140 mn by 2034 globally based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Sulopenem Etzadroxil Overview
Sulopenem etzadroxil (PF-03709270) is under development for the treatment of complicated urinary tract infections, uncomplicated urinary tract infections (uUTI), complicated intra-abdominal infections, community-acquired bacterial pneumonia, pelvic inflammatory disease and bacterial infections like acute bacterial prostatitis, gonococcal urethritis. The drug candidate is a penem beta-lactam antibiotic. It is administered through oral route. The drug candidate is a prodrug of sulopenam (CP-70,429). It acts by targeting penicillin binding protein (PBP).
Iterum Therapeutics Overview
Iterum Therapeutics is a clinical-stage pharmaceutical company. It develops anti-infectives for multi-drug resistant (MDR) pathogens for treating serious and life-threatening diseases. The company mainly develops Sulopenem, an oral and IV targeted-spectrum penem antibiotic for the treatment of infections caused by multi-drug resistant, gram-negative bacteria in both the hospital and community environments. Iterum Therapeutics seeks to work in partnership with other pharmaceutical companies for product development and commercialization opportunities. The company has operations with research and development facility in the US. Iterum Therapeutics is headquartered in Dublin, Ireland.
The operating loss of the company was US$24.5 million in FY2021, compared to an operating loss of US$34.6 million in FY2020. The net loss of the company was US$91.6 million in FY2021, compared to a net loss of US$52 million in FY2020.
For a complete picture of Sulopenem Etzadroxil’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.