T-Cell therapy is under clinical development by Vaccinex and currently in Phase I for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+ Breast Cancer). According to GlobalData, Phase I drugs for Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer (HER2+ Breast Cancer) have an 86% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how T-Cell therapy’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
T-Cell therapy overview
Cell therapy is under development for the treatment of metastatic HER2-positive breast cancer. It consists of IL-15 expanded CD4 T cells and is administered through intravenous route.
Vaccinex is a clinical-stage biotechnology company. It discovers and develops targeted biotherapeutics to treat neurodegenerative diseases, cancer and autoimmune disorders. The company’s lead platform technologies include antibody platform and ActivMAb, SEMA4D, and antibody discovery platform. Vaccinex through its antibody platform develops its lead product candidate VX15, for the treatment of various indications such as neurodegenerative diseases, neuroinflammatory, and cancer. The company also develops VX5 that is in preclinical development for the treatment of autoimmune disorders. It has partnership with biotechnology and biopharmaceutical companies to enhance its product candidates. Vaccinex is headquartered in Rochester, New York, the US.
For a complete picture of T-Cell therapy’s drug-specific PTSR and LoA scores, buy the report here.