The Tauopathies drugs in development market research report provides comprehensive information on the therapeutics under development for Tauopathies, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses key aspects of the companies and drugs in development for Tauopathies. Buy the report here.
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The report also covers the descriptive pharmacological action of the therapeutics and the latest news and press releases. Additionally, the report provides an overview of the key players involved in therapeutic development for Tauopathies and features dormant and discontinued products.
GlobalData tracks 51 drugs in development for Tauopathies by 44 companies/universities/institutes. The top development phase for Tauopathies is preclinical with 28 drugs in that stage. The Tauopathies pipeline has 40 drugs in development by companies and 11 by universities/ institutes. Some of the companies in the Tauopathies pipeline products market are: Korea Institute of Science and Technology, Biosplice Therapeutics and Oligomerix.
The key targets in the Tauopathies pipeline products market include Microtubule Associated Protein Tau, Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A, and Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1B.
The key mechanisms of action in the Tauopathies pipeline product include Microtubule Associated Protein Tau Inhibitor with 24 drugs in Phase II. The Tauopathies pipeline products include six routes of administration with the top ROA being Oral and ten key molecule types in the Tauopathies pipeline products market including Small Molecule, and Monoclonal Antibody.
Tauopathies overview
Tauopathies are a group of neurodegenerative disorders characterized by the aggregation of tau protein into neurofibrillary or gliofibrillary tangles in the human brain. Tau protein normally stabilizes microtubules, which are essential for intracellular transport and communication. However, when tau becomes hyperphosphorylated or misfolded, it dissociates from microtubules and forms insoluble aggregates that impair neuronal function and survival. Tauopathies can present with various clinical phenotypes, such as cognitive impairment, behavioral changes, dementia, parkinsonism, and language disorders. Tauopathies can be classified based on the predominant tau isoforms that are present in the inclusions (3R, 4R or equal 3R:4R ratio). Tau biomarkers in cerebrospinal fluid and blood, as well as imaging techniques, can help in the diagnosis and evaluation of tauopathies. Currently, there is no effective treatment for tauopathies, but several tau-targeted therapies are in development.
For a complete picture of Tauopathies’s pipeline drug market, buy the report here.
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GlobalData’s pipeline drugs offers detailed profiles of pharmaceutical drugs in all stages of pre-clinical and clinical development, from discovery through to pre-registration. Coverage is limited to novel human medicinal drugs and biosimilars seeking market approval proprietary and is one of two primary repositories of pharmaceutical drug information offered by GlobalData through its Pharmaceutical Intelligence Center.
