Towa Pharmaceutical has filed a patent for masking particles that suppress drug release in the oral cavity and pharynx, releasing rapidly after swallowing. The particles contain a drug of a salt with an acid and a carbonate, coated with a water-insoluble polymer. GlobalData’s report on Towa Pharmaceutical gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Towa Pharmaceutical, Nanoparticle drug conjugates was a key innovation area identified from patents. Towa Pharmaceutical's grant share as of January 2024 was 22%. Grant share is based on the ratio of number of grants to total number of patents.

Controlled release drug particles with water-insoluble polymer coating

Source: United States Patent and Trademark Office (USPTO). Credit: Towa Pharmaceutical Co Ltd

The patent application (Publication Number: US20240016745A1) describes a novel approach to masking particles containing drugs by utilizing a drug-containing particle with a salt and acid, along with a carbonate, coated with a water-insoluble polymer. The carbonate component can be a water-soluble carbonate and is present in specific amounts relative to the drug-containing particles. The coating layer's content is also defined in relation to the drug-containing particles, ensuring precise control over the drug's release. The particles can be uniform or structured with separate portions for the drug and carbonate, allowing for customization in drug delivery mechanisms.

Furthermore, the patent application extends to the production of tablets, capsules, granules, fine granules, or powders incorporating these masking particles. Additionally, an orally disintegrating tablet formulation is detailed, showcasing the versatility of the technology. The methods outlined in the patent application provide a systematic approach to controlling the dissolution and release of drugs, offering a potential solution for enhancing drug delivery efficiency and efficacy. Overall, the innovative approach presented in the patent application has the potential to revolutionize drug delivery systems, providing a more controlled and efficient means of administering medications.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies