The Tyrosine Protein Kinase ABL1 pipeline drugs market research report outlays comprehensive information on the Tyrosine Protein Kinase ABL1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Tyrosine Protein Kinase ABL1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Central Nervous System, Oncology, Respiratory, and Gastrointestinal which include the indications Parkinson’s Disease, Lewy Body Dementia, Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia), Oncology, Idiopathic Pulmonary Fibrosis, Constipation, and Dysphagia. It also reviews key players involved in Tyrosine Protein Kinase ABL1 targeted therapeutics development with respective active and dormant or discontinued products.
The Tyrosine Protein Kinase ABL1 pipeline targets constitutes close to 14 molecules. Out of which, approximately 12 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase II, Phase I, and Preclinical stages are 1, 5, 1, and 5 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 1, and 1 molecule.
Tyrosine Protein Kinase ABL1 overview
Tyrosine protein kinase ABL1 (ABL1) is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias.
For a complete picture of Tyrosine Protein Kinase ABL1’s drug pipeline, buy the report here.
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