The Tyrosine Protein Phosphatase Non Receptor Type 1 pipeline drugs market research report outlays comprehensive information on the Tyrosine Protein Phosphatase Non Receptor Type 1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Tyrosine Protein Phosphatase Non Receptor Type 1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, Metabolic Disorders, Central Nervous System, and Genetic Disorders which include the indications Unspecified Cancer, Solid Tumor, Type 2 Diabetes, Obesity, Alzheimer’s Disease, Rett Syndrome, Duchenne Muscular Dystrophy, and Wilson Disease. It also reviews key players involved in Tyrosine Protein Phosphatase Non Receptor Type 1 targeted therapeutics development with respective active and dormant or discontinued products.
The Tyrosine Protein Phosphatase Non Receptor Type 1 pipeline targets constitutes close to 21 molecules. Out of which, approximately 12 molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase I, IND/ CTA Filed, Preclinical, and Discovery stages are 4, 1, 3, and 4 respectively. Similarly, the universities portfolio in Preclinical, and Discovery comprises 5, and 4 molecule.
Tyrosine Protein Phosphatase Non Receptor Type 1 overview
Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme encoded by the PTPN1 gene. It acts as a regulator of endoplasmic reticulum unfolded protein response. It plays an important role in CKII- and p60c-src-induced signal transduction cascades. It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. It mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. It regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
For a complete picture of Tyrosine Protein Phosphatase Non Receptor Type 1’s drug pipeline, buy the report here.
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