Unichem Laboratories has been granted a patent for a novel key intermediate in the synthesis of rivaroxaban. The invention includes a crystalline form of the intermediate and an improved process for preparing rivaroxaban. GlobalData’s report on Unichem Laboratories gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Unichem Laboratories, Peptide pharmacophores was a key innovation area identified from patents. Unichem Laboratories's grant share as of February 2024 was 46%. Grant share is based on the ratio of number of grants to total number of patents.

Intermediate for efficient preparation of rivaroxaban

Source: United States Patent and Trademark Office (USPTO). Credit: Unichem Laboratories Ltd

A recently granted patent (Publication Number: US11891384B2) discloses a novel compound, 4-{4-[(5S)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]-phenyl}-morpholin-3-one perchlorate, as claimed in the first two claims. The patent further describes a specific crystalline form of this compound, characterized by a DSC peak at 206.84°C, as outlined in claim 3. Additionally, claim 4 details the XRPD pattern of this crystalline form, with specific 2? values at 10.26, 13.70, 19.67, 20.37, 23.08, and 24.76+/-0.2?.

This patent highlights the unique chemical composition and crystalline structure of 4-{4-[(5S)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]-phenyl}-morpholin-3-one perchlorate, providing valuable insights into its physical properties. The detailed characterization of the compound's crystalline form through DSC and XRPD analysis sets a foundation for potential applications in various fields, including pharmaceuticals, materials science, and beyond. The precise identification of the compound's structural features opens up avenues for further research and development, showcasing the innovative nature of this patented invention.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies