Yield10 Bioscience has been granted a patent for transgenic plants with enhanced yield and seed yield. The plants are transformed with transgenic polynucleotides encoding metabolic enzymes, resulting in unprecedented increases in seed yield. The claim involves plants with heterologous enzymes like pyruvate carboxylase and malate synthase, showing improved properties. GlobalData’s report on Yield10 Bioscience gives a 360-degree view of the company including its patenting strategy. Buy the report here.

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According to GlobalData’s company profile on Yield10 Bioscience, Genetically engineered pesticides was a key innovation area identified from patents. Yield10 Bioscience's grant share as of April 2024 was 57%. Grant share is based on the ratio of number of grants to total number of patents.

Transgenic plants with enhanced seed yield and oil content

Source: United States Patent and Trademark Office (USPTO). Credit: Yield10 Bioscience Inc

A recently granted patent (Publication Number: US11965182B2) discloses a transgenic plant containing two or more heterologous enzymes, each encoded by a transgene. Specifically, the plant includes a pyruvate carboxylase (Pyc) and a malate synthase (AceB), leading to increased properties such as seed yield or seed oil content compared to non-transgenic plants of the same species. The transgene for each enzyme includes a nucleotide sequence directing them to the plastids of the plant, with expression driven by a seed-specific promoter.

Moreover, the transgenic plant, which can be derived from various species including camelina, Brassica, soybean, and others, exhibits property increases ranging from 15% to as high as 300% compared to non-transgenic counterparts. Additionally, the patent covers the inclusion of a heterologous bicarbonate transporter transgene and a Chlamydomonas reinhardtii CCP1 gene in the transgenic plant. The patent also details the specific sequences for the pyruvate carboxylase enzyme from various bacterial sources like Bacillus subtilis, Salinibacillus aidingensis, and Bacillus pumilus. The patent further outlines a method for creating and selecting transgenic plants with enhanced properties, involving the growth of transgenic plants, property measurement, and selection based on the desired increase compared to wild-type plants.

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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies