ZB-131 is under clinical development by ZielBio and currently in Phase II for Gallbladder Cancer. According to GlobalData, Phase II drugs for Gallbladder Cancer have a 33% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how ZB-131’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ZB-131 overview

ZB-131 is under development for the treatment of solid tumors including pancreatic ductal adenocarcinoma, ovarian cancer, pancreatic ductal adenocarcinoma and metastatic biliary tract cancer including extrahepatic bile duct cancer, gallbladder cancer. It is a humanized monoclonal antibody which acts by targeting cell surface plectin (CSP). The drug candidate is developed based on Zielfind platform. It is administered through intravenous route.

ZielBio overview

ZielBio, Inc., is a biotechnology company that identifies high value disease targets and develops therapeutic interventions to improve patient outcomes. The company is headquartered in United States.

For a complete picture of ZB-131’s drug-specific PTSR and LoA scores, buy the report here.


GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in its clinical pathway (PTSR), as well as how likely the drug will be approved (LoA). This is based on a proprietary algorithm built from the drugs’ sales forecast, regulatory milestones, cost forecasts, WACC rate and other proprietary data sources found on GlobalData’s Pharmaceutical Intelligence Center.