Skip to site menu Skip to page content

Spheroids in Motion: Scalable & Streamlined Assays for 3D Cancer Models

By Kugelmeiers - Regenerative Medicine. Vision. Mission.
The mechanical properties of cells and tissues have gained attention for their importance in physiology and pathology. However, there are obstacles to transferring the growing bulk of mechanobiological knowledge from 2D to the more current 3D models. By combining the ferrule-top nanoindentation technology of Pavone and the micro-structured culture surfaces of Sphericalplate 5D® (SP5D, Kugelmeiers), we measured the mechanics of hundreds of uniformly sized prostate cancer spheroids in their original culture plate. Additionally, we reproduced in 3D settings the changes in mechanical properties induced in 2D culture by cytoskeletal-targeting compounds. To read more, please download this free white paper.
Enter your details below to view the free white paper

By downloading this whitepaper, you acknowledge that GlobalData may share your information with our white paper partners/sponsors who may contact you directly with information on their products and services.

Visit our Privacy Policy for more information about our services, how GlobalData may use, process and share your personal data, including information on your rights in respect of your personal data and how you can unsubscribe from future marketing communications. Our services are intended for corporate subscribers and you warrant that the email address submitted is your corporate email address.

Related Content