Laser Diffraction and Automated Imaging: Complementary Techniques for Nasal Spray Development

Nasal spray products are increasingly valued for delivering systemic, as well as locally acting therapies, most notably hormone and migraine treatments.

The large surface area and rich blood supply of the nasal passages aid the rapid absorption of drug entities, with their close proximity to the central nervous system being of particular benefit.

The regulatory guidance for nasal sprays emphasises the importance of testing the device and the formulation together since it is in combination that they define the unique characteristics of the delivered dose.

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