As manufacturing models evolve to embrace quality by design and process analytical technology, pharmaceutical companies are increasingly reassessing the way they produce drugs. In this issue we look at technological advances in the area of manufacturing and APIs and explore some of the challenges and issues faced by companies working in this sector.
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We find out how continuous manufacturing could revolutionise operations in the pharma industry, and explore the best recipes for successful outsourcing relationships with CMOs in emerging markets. As the market for API manufacturing becomes ever more competitive, we find out how specialist contractors can stay ahead of the game, and investigate efforts being made on a global scale to control the quality of APIs.
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In this issue
Checked and Certified
Good-quality active pharmaceutical ingredients are vital to the production of good quality medicines. Dr Antony Fake and Jacqueline Sawyer explain how the World Health Organization’s Prequalification of Medicines Programme facilitates access to quality medicines through assessment of products and inspection of manufacturing sites.
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Smarter, Faster, Cheaper
Pharmaceutical companies are increasingly enlisting the help of API contract manufacturers to improve efficiencies. But as the field becomes more and more competitive, how can specialist contractors ensure they don’t get left behind? We catch up with Almac Group’s Denis Geffroy to find out.
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By GlobalDataOn the Right Track
Excipients can enhance product performance, patient acceptability and compliance, but some also interact with the active ingredient, thereby compromising performance. We ask Professor Luigi G Martini of King’s College London and Patrick Crowley of Callum Consultancy how pharma manufacturers can select the right excipient for their formulation.
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Going with the Flow
As manufacturing models increasingly embrace process analytical technology, big pharma needs to reassess the way it produces drugs. We investigate how continuous manufacturing will revolutionise operations in years to come.
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Lost in Translation
Communication is an essential but often tricky element of outsourcing business to emerging markets. We ask Novo Nordick’s Him Steffensen how to successfully work with CMOS in emerging markets.
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Green Leaders
While some industries still talk about going sustainability, the pharmaceutical sector is already there. We ask the team at Pfizer about the significant strides the company has made in both green chemistry and green operations.
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Next Issue: packaging and labelling
Pharmaceuticals place high demands on packaging, allowing the industry to show off its most advanced technology. In the next issue we look at the latest developments in this sector.
One promising new packaging solution comes in the form of phase change materials that can transform to enhance cooling. We investigate if they could represent a breakthrough for the transport of temperature-sensitive drugs in areas with limited access to refrigeration.
We also check in on efforts to tighten up track & trace through the adoption of standard laws in the EU and further afield, and find out how smart packaging could help to improve patient communication and compliance.
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