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Vaccines for Alzheimer’s: exploiting similarities with Down syndrome

One approach to overcome continuing challenges facing drug research and development for Alzheimer’s is a vaccine. Swiss AC Immune has developed an Abeta-focused vaccine called ACI-24, which has been both effective and safe in pre-clinical models. As well as studying ACI-24 in Alzheimer’s patients, the company is investigating the candidate in Down syndrome patients who have a genetic predisposition to developing Alzheimer’s and are a more homogenous patient group.

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