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June 8, 2020

AbbVie and partners to develop monoclonal antibody against Covid-19

AbbVie has partnered with Harbour BioMed (HBM), Utrecht University (UU) and Erasmus Medical Center (EMC) to develop a monoclonal antibody therapeutic for the prevention and treatment of Covid-19.

AbbVie has partnered with Harbour BioMed (HBM), Utrecht University (UU) and Erasmus Medical Center (EMC) to develop a monoclonal antibody therapeutic for the prevention and treatment of Covid-19.

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by GlobalData
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AbbVie and its collaborators will advance a fully human, neutralising antibody, 47D11, which acts on Covid-19 through the conserved domain of the SARS-CoV-2’s spike protein, discovered by HBM, UU and EMC.

As part of the alliance, AbbVie will work with HBM, UU and EMC through the preclinical activities and will make preparations for late-stage preclinical and clinical development.

Furthermore, AbbVie will get an option to exclusively licence the antibody from the three partners for clinical development and commercialisation globally.

AbbVie Research and Development senior vice-president and chief scientific officer Tom Hudson said: “The antibody discovered by UU, EMC and Harbour BioMed is extremely promising based on the mechanism by which it targets the virus and on its developability as a fully human protein.

“We look forward to working with this outstanding team to advance this antibody towards clinical trials.”

HBM noted that the partnership with AbbVie will help speed-up the advancement of the monoclonal antibody therapeutic into clinical trials.

Harbour BioMed founding chief scientific officer Frank Grosveld said: “The collaboration is an endorsement of our approach to fully human antibody discovery and development. Through this collaboration, we are well-positioned to move rapidly towards clinical trials.”

In cell culture studies, the antibody blocked infection by the SARS-CoV-2 and also SARS-CoV, which is also a type of coronavirus. The Nature Communications journal published the antibody discovery.

In March, Israel health ministry approved the licensing of a generic version of AbbVie’s HIV drug Kaletra to treat Covid-19. The patent for the anti-viral drug Kaletra expires in Israel in 2024.

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Free Whitepaper
img

What is the impact of China’s Zero-COVID lockdowns on economic activity, consumer goods and the foodservice industry?

While wanting to protect the country from being overwhelmed by Omicron, China’s adherence to a Zero-COVID policy is resulting in a significant economic downturn. COVID outbreaks in Shanghai, Beijing and many other Chinese cities will impact 2022’s economic growth as consumers and businesses experience rolling lockdowns, leading to a slowdown in domestic and international supply chains. China’s Zero-COVID policy is having a demonstrable impact on consumer-facing industries. Access GlobalData’s new whitepaper, China in 2022: the impact of China’s Zero-COVID lockdowns on economic activity, consumer goods and the foodservice industry, to examine the current situation in Shanghai and other cities in China, to better understand the worst-affected industry sectors, foodservice in particular, and to explore potential growth opportunities as China recovers. The white paper covers:
  • Which multinational companies have been affected?
  • What is the effect of lockdowns on foodservice?
  • What is the effect of lockdowns on Chinese ports?
  • Spotlight on Shanghai: what is the situation there?
  • How have Chinese consumers reacted?
  • How might the Chinese government react?
  • What are the potential growth opportunities?
by GlobalData
Enter your details here to receive your free Whitepaper.

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