View all newsletters
Receive our newsletter - data, insights and analysis delivered to you
  1. News
October 28, 2020updated 02 Dec 2021 5:57am

Apellis enters drug development and commercialisation deal with Sobi

Apellis Pharmaceuticals has entered into a strategic collaboration with Swedish Orphan Biovitrum (Sobi) to fast-track the advancement of systemic pegcetacoplan to treat multiple rare diseases with high unmet need.

Apellis Pharmaceuticals has entered into a strategic collaboration with Swedish Orphan Biovitrum (Sobi) to fast-track the advancement of systemic pegcetacoplan to treat multiple rare diseases with high unmet need.

Free Report
img

2022: So far In Venture Capital

Global investment in 2022 has been majorly dominated by North America, Europe, and Asia Pacific, whereas the Middle East, and South and Central America have recorded low investments comparatively. In light of this, Europe and North America have been identified as the major destinations for Private Equity and Venture Capital (PE/VC) investments.   GlobalData’s whitepaper analyzes which sectors PE/VC firms have been investing in, looking at Technology, Media, and Telecom, with these sectors recording $356 billion and a deal volume of over 10,000 deals in 2022. Healthcare, Financial Services, Business & Consumer Services, and Construction sectors have also seen high investment activity by PE/VC firms, recording a deal value of over $70 billion each.   But what can this mean for you?   Understand how the Deals Database on GlobalData Explorer can be leveraged to:  
  • Track the Aggregate Investment Volumes in PE/VC-Stage firms across geographies and sectors, in addition to viewing the specific deals that drove these volumes
  • Identify the top investors already active in any sector-Geography combinations
  • Assess the Performance of Financial and Legal Advisors, supporting the Dealmaking in any segment of choice (Customizable League tables)
  • Understand what is driving the PE/VC fundraising (Deal Rationale)
  Consult our full report here and optimize your business strategy.
by GlobalData
Enter your details here to receive your free Report.

Apellis will receive an upfront payment of $250m from Sobi and is eligible to get up to $915m as milestone payments, along with tiered double-digit royalties on sales.

Under the deal, Sobi will also provide $80m in reimbursement payments over four years for research and development to support the initial development plan.

Apellis Pharmaceuticals co-founder and CEO Cedric Francois said: “This collaboration enables us to further expand on the broad platform potential of targeting C3 for serious rare diseases that impact hundreds of thousands of patients around the world.

“Together, we will quickly advance systemic pegcetacoplan in multiple registrational programmes across haematology, nephrology, and neurology while also preparing for our first potential US launch in PNH.”

Pegcetacoplan targets excessive activation of C3 in the complement cascade, part of the immune system, which can aid in progression of serious ailments.

Together, the companies will advance systemic pegcetacoplan in five parallel registrational programmes including two new haematological studies, CAD and HSCT-TMA, set to start next year.

These include ongoing programmes in haematology (PNH), nephrology (IC-MPGN/C3G) and neurology (ALS).

According to the deal, Sobi will get global co-development and exclusive ex-US commercialisation rights for systemic pegcetacoplan.

Apellis will retain US commercialisation rights for systemic pegcetacoplan and worldwide commercial rights for ophthalmological pegcetacoplan, which is in Phase III trials for geographic atrophy (GA).

Apellis will take care of all regulatory and commercial activities in the US and the ongoing marketing authorisation application (MAA) review for PNH in the European Union, which will be later transferred to Sobi.

Sobi will handle all regulatory and commercial activities for systemic pegcetacoplan in ex-US markets.

In April, Sobi released the 2020 Haemophilia Index, a report that analyses the quality of life of patients treated for haemophilia in Europe.

Related Companies

Free Report
img

2022: So far In Venture Capital

Global investment in 2022 has been majorly dominated by North America, Europe, and Asia Pacific, whereas the Middle East, and South and Central America have recorded low investments comparatively. In light of this, Europe and North America have been identified as the major destinations for Private Equity and Venture Capital (PE/VC) investments.   GlobalData’s whitepaper analyzes which sectors PE/VC firms have been investing in, looking at Technology, Media, and Telecom, with these sectors recording $356 billion and a deal volume of over 10,000 deals in 2022. Healthcare, Financial Services, Business & Consumer Services, and Construction sectors have also seen high investment activity by PE/VC firms, recording a deal value of over $70 billion each.   But what can this mean for you?   Understand how the Deals Database on GlobalData Explorer can be leveraged to:  
  • Track the Aggregate Investment Volumes in PE/VC-Stage firms across geographies and sectors, in addition to viewing the specific deals that drove these volumes
  • Identify the top investors already active in any sector-Geography combinations
  • Assess the Performance of Financial and Legal Advisors, supporting the Dealmaking in any segment of choice (Customizable League tables)
  • Understand what is driving the PE/VC fundraising (Deal Rationale)
  Consult our full report here and optimize your business strategy.
by GlobalData
Enter your details here to receive your free Report.

NEWSLETTER Sign up Tick the boxes of the newsletters you would like to receive. A weekly roundup of the latest news and analysis, sent every Friday. The pharmaceutical industry's most comprehensive news and information delivered every month.
I consent to GlobalData UK Limited collecting my details provided via this form in accordance with the Privacy Policy
SUBSCRIBED

THANK YOU

Thank you for subscribing to Pharmaceutical Technology