SOM Biotech has completed in-vitro analyses and identified three drug candidates that can be potentially used to treat Covid-19.

The three candidates inhibit the main protease of SARS-CoV-2, which causes Covid-19, in turn targeting the virus’ replication.

SOM Biotech partnered with Ewha Woman’s University in South Korea for Covid-19 research.

The company’s artificial intelligence (AI)-based screening technology, SOMAIPRO, was used to discover the inhibitors of 3CL proteases of SARS-CoV-2, SARS-CoV and MERS-CoV. These inhibitors were intended to offer potential Covid-19 treatments.

Ewha Woman’s University professor Dong-Hae Shin said: “We are very proud about working on promising Covid-19 treatments and contributing to finding effective, safe and fast solutions due to the importance of the current pandemic situation.

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“We decided to start working with SOM Biotech as we are committed to tackling this Covid-19 pandemic leveraging on partners with innovative technologies and excellent know-how.”

Of the three in-vitro validated candidates, Eravacycline is an approved drug while Prexasertib is currently in clinical development and Cynarine is a natural compound used as a dietary supplement.

All three drug candidates can be repurposed to treat Covid-19, said the company.

The company also filed a patent application for method-of-use protection for the three compounds globally.

SOM Biotech CEO and founder Raul Insa said: “We have joined forces with professor Dong-Hae Shin from Ewha Woman’s University to combine our scientific and medical expertise to find new therapies for the treatment of Covid-19.

“Thanks to our capabilities in screening molecules with our AI-based technology, we have validated active anti-coronavirus compounds. Thus, we look forward to the rapid development of these drugs to be able to provide patients with an effective and safe treatment against the Covid-19 as soon as possible.”

The company said that clinical studies of these drug candidates can be launched immediately.