Takeda has concluded the previously announced acquisition of the complete shares of Nimbus Therapeutics’ tyrosine kinase 2 (TYK2) programme subsidiary Nimbus Lakshmi.
The latest move comes following clearance from the United States Federal Trade Commission and after satisfaction of other conditions related to the deal closure.
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Takeda originally signed the acquisition agreement in December last year.
According to the agreement and following the deal completion, Nimbus will receive nearly $4bn in upfront payment from Takeda.
This payment will be made after adjusting items including closing account payable and closing indebtedness of Lakshmi.
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Additionally, Nimbus is eligible for two milestone payments of $1bn each from Takeda after achieving $4bn in annual net sales and $5bn of products developed from the TAK-279 programme.
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By GlobalDataTakeda global portfolio division president Ramona Sequeira said: “With our plan to acquire announced in December, we are excited to have promptly added TAK-279, a highly selective oral TYK2 inhibitor with truly transformative potential for patients in multiple diseases, to our late-stage pipeline.
“This programme closely aligns with our strategy and expertise in immune-mediated diseases, and we look forward to sharing more details of our development plans soon.”
With this transaction, Takeda has now acquired TAK-279, formerly known as NDI-034858 at Nimbus.
Phase III clinical trial of TAK-279 in psoriasis is expected to commence this year.
TAK-279 is said to have the potential to demonstrate safety, efficacy and convenience in psoriasis and other immune-mediated diseases.
These diseases include psoriatic arthritis, inflammatory bowel disease and systemic lupus erythematosus.
Takeda noted that the acquisition would boost its growing late-stage pipeline while expanding its portfolio.
