Last month, after close to a year of project time, a German producer of generic...
LB Bohle has been the technological leader for all film coating applications for more than 15 years.
Bohle Coaters guarantee excellent product processing with the highest profitability. We assert our leading role through continuous developments and patented advantages.
Film coating processes can be divided into three basic operations: mixing, spraying, drying. Each step is carefully engineered and optimized to coordinate with the others. Bohle Coaters offer the best combination of the processing operations on the market.
One essential but basic operation in coating is tablet bed mixing. Each tablet moves uniformly under the spray. This movement, however, must be done carefully and with minimal mechanical stress to avoid damaging delicate tablets. The perfect choice is an elongated coating pan with continuously welded spirals as mixing elements. Spirals guarantee constant and careful mixing. Because of the elongated pan, the flat tablet bed ensures minimum static pressure and very careful handling of sensitive tablets.
Apart from the coating liquid, two other aspects must be considered. First, the spraying equipment: nozzle type, number of nozzles and nozzle-to-nozzle distance. Second, the process parameters: nozzle-to-bed distance, angle spray rate, atomizing and pattern air pressure.
Coating nozzles are the key to efficient coating. The adjustable oval spray pattern and so-called “anti-bearding caps” are currently state of the art. Another key factor is the design of the nozzle-to-nozzle distance.
The Bohle coaters offer the best energy transfer and mass transfer (evaporation) analogue to a packed-bed reactor. Once the coating liquid has reached the tablet, the coating should dry quickly and evenly.
To ensure rapid drying, supply air is directed through the pan perforations into the tablet bed. Significant parameters include the supply air temperature and humidity, supply air volume and pan perforations. Excessive moisture or spray drying can be prevented with the appropriate settings. Spray drying, in particular, frequently accompanies coating.
The drying performance can be influenced and optimized through the type of air flow
in the coater. Directing supply air and exhaust air through the tablet bed reduces turbulence and creates a cold environment in the spraying area. This internal dynamic prevents spray drying.
Film Coater BFC – The technological leader
The high-end version of the Bohle coater designed specifically for high speed, problem-free coating, providing unparalleled tablet uniformity and efficiencies. A high containment execution is also available.
- State of the art coating technology
- Homogeneous mixing due to patented spirals
- Gentle mechanical treatment of tablet cores to avoid edging and breaking
- Simple and quick discharging by reversing the direction of rotation
- Nozzles with AB-caps ensure long-enduring operation
- Geometrical similarities of all machine sizes ensure secure scale-up conditions
- Unique cleaning abilities with integrated high-pressure washing-system
- High sophisticated control system
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