Solvent evaporation and concentration of active substances are essential steps in the drug discovery process.

Rotary evaporation is used for synthesis, development, sample preparation, solvent recycling and scale-up production on the quest to novel therapeutics.

Our industry-leading rotary evaporation solutions cover the complete sample range and are ideal for simple scale-up from lab scale to production scale projects. A high degree of automation and cutting-edge design combine to offer reliability and convenience in the pharma R&D laboratory.

Parallel evaporation enables sample throughput of 4 to 96 samples per batch with sample amounts ranging from 1 to 500 ml per sample.

We are market leaders at laboratory vacuum evaporation, where you can concentrate samples with sizes between 1 and 2.5 L.

BUCHI can also support you with industrial-scale evaporation of up to 20 L in batch-wise or continuous operation mode.

Rotavapor® R-300: efficient and convenient laboratory rotary evaporation

The R-300 is the industry-leading solution for laboratory evaporation. The system combines convenience and versatility to match your specific needs.

Select benefits of the Rotavapor® R-300:

• Fully modular system with a selection of heating baths, vacuum pumps, recirculating chillers, condensers, glassware and more to suit your particular application
• Precise control of all system parts, including heating bath, vacuum pump and recirculating chiller through a central interface
• Traceability of all process parameters, including data recording and generation of graphs
• Remote control possibilities with instant alerts on mobile devices in cases of process deviation
• One-click distillations with unique features such as automatic foam detection, automatic distillations
• Convenient use with patented Combi-Clip that allows connection of evaporation flask with one hand

Rotavapor® R-220 Pro: highest flexibility in the production of therapeutics on a larger scale

The Rotavapor® R-220 Pro family includes four platforms designed to meet the needs of scale-up and production laboratories

Select benefits of Rotavapor® R-220 models:

• Programmable custom standard operation procedures (SOPs) with remote control possibilities through mobile phone devices or personal computers
• Continuous operation thanks to sturdy equipment design, automatic draining and refilling
• Automatic distillations possible even of challenging samples that foam easily
• Superior safety guaranteed by plastic coated glassware (P+G), protection shields and grids
• User-friendly flask handling with patented flask coupling and flask handler
• Products free of contamination through the use of inert materials
• Extended lifetime of the instrument thanks to exclusive use of corrosion-free stainless steel
• Seven glass assemblies for various applications such as distillation of foaming samples, recrystallization under reflux or operation under height restrictions

Syncore® Polyvap – evaporate up to 96 samples at once for ultimate time-saving benefits

Syncore® Polyvap offers the highest sample throughput of up to 96 samples simultaneously due to vacuum vortex parallel evaporation technology

• Interchangeable racks for sample volumes from 0.5 to 500 mL
• Adjustable vacuum gradients
• Zero cross-contamination due to vacuum cover
• Reduced costs and emissions by eliminating nitrogen use
• Time savings due to no boiling retardation thanks to variable orbital shaking