Merck obtains favourable US court ruling on sitagliptin patent lawsuit
In the latest ruling, the court determined that both of the Merck patents at issue were legitimate and infringed.
Metabolic Disorders
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Metabolic Disorders
Rivus raises $132m to advance clinical development of obesity treatment
In a Phase IIa metabolic study in obese subjects, HU6 substantially lowered liver, visceral and total body fat.
How environmental factors could influence disease and drugs
Environmental and social exposures can majorly affect human health, and researchers are now finding ways to use that understanding in…
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FDA grants Orphan Drug status to Maze’s Pompe disease treatment
MZE001 is being assessed in a Phase I trial to evaluate the tolerability, safety, pharmacokinetics and pharmacodynamics.
FDA grants Rare Pediatric Disease status for iECURE’s OTC deficiency therapy
The gene editing approach of the company is based on delivering twin adeno-associated virus capsids with varying payloads.
Alnylam identifies gene to lower abdominal fat and decrease cardiovascular risk
Alnylam aims to develop a therapy that targets the INHBE gene and reduces the overall risk of T2D and coronary…
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FDA grants Orphan Drug status to Aro Biotherapeutics’ Pompe disease therapy
The company plans to advance ABX1100 into clinical trials in the middle of next year.
Lilly announces results from SURPASS programme for T2D and obesity therapy Mounjaro
Further trials for pediatric and heart failure patients are currently ongoing.
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