Pfizer and BioNTech have said a laboratory test has shown that three doses of their Covid-19 vaccine, Comirnaty, can neutralise the SARS-CoV-2 Omicron variant. An assessment showed that sera from individuals who received the third dose a month ago neutralised the Omicron variant to levels seen for the wild-type SARS-CoV-2 spike protein after two doses. At the same time, two doses of the vaccine resulted in lower neutralising antibodies, indicating that a booster shot is necessary to prevent infection.

French biotech company Valneva has signed an advance purchase agreement to supply one million doses of its inactivated Covid-19 vaccine candidate VLA2001 to Bahrain. The move comes as the company commences a rolling submission process with the National Health Regulatory Authority in the country. Last month, Valneva signed a similar agreement with European Commission to deliver up to 60 million doses of VLA2001.

The National Medical Products Administration (NMPA) of China has approved Brii Biosciences’ monoclonal neutralising antibody therapy for Covid-19. The amubarvimab/romlusevimab combination was approved for treating at-risk adults and minors aged 12-17, weighing at least 40kg and suffering from mild to moderate Covid-19. The NMPA approval comes after the company reported positive results from a study with 847 enrolled outpatients. Brii Bio has also filed emergency use authorisation for the combination in the US.