Join Our Newsletter - Get important industry news and analysis sent to your inbox – sign up to our e-Newsletter here

Laboratoria Smeets

Contract Manufacturing of Pharmaceutical Powders and New Technology for API Solubility and Bioavailability

Fotografielaan 42,
B-2610 Antwerpen-Wilrijk Other,

Fotografielaan 42,
B-2610 Antwerpen-Wilrijk Other,

Laboratoria Smeets is a Belgian company with more than 30 years of experience in contract manufacturing and contract packing activities for pharmaceutical and para-pharmaceutical products.

The company is located near Antwerp on a site that totals 4,200m². All of the company’s production and packing activities are performed under current good manufacturing practice (cGMP) conditions.

Continuous production of water-soluble granules via twin screw granulation

Laboratoria Smeets has developed, in collaboration with Ghent University, a technique to produce water-soluble granules containing poorly water soluble drugs of Class II (poorly soluble, highly permeable) or Class IV (poorly soluble, poorly permeable) of the Bio Classification System (BCS).

The faster release of the active pharmaceutical ingredients (API) often results in an improved bioavailability and consequently a decreased intake of API to obtain the same clinical effect.

Formulation, mixing and packaging of pharmaceutical powders and liquids

Laboratoria Smeets’ core capabilities are powder formulation and mixing; liquid formulation and mixing; and packaging of liquids and powders.

The company’s core end-products are sachets of powders, liquids, and tablets; containers (glass and plastic) of liquids and powders; and the filling of powders in bags.

Its goals are:

  • To perform pharmaceutical mixing and packaging according to good manufacturing practice (GMP) guidelines
  • To develop cost-efficient and user-friendly solutions for pharmaceutical packaging
  • To provide creative packaging ideas jointly with our customers

Contract manufacturing and mixing of pharmaceutical powders and liquids

As part of our contract manufacturing services, Laboratoria Smeets can perform mixing activities for powders and liquids.

Contract packing of pharmaceutical powders and liquids

Laboratoria Smeets offers contract packing of pharmaceutical powders and liquids, including the following services:

  • Sachet packing of powders and liquids
  • Sachet packing of tablets and capsules
  • Bottle and container filling
  • Barcode labelling
  • Repacking activities

QC analysis, QC release, product development and stability studies

Laboratoria Smeets can provide the following contract services:

  • Product development
  • Stability studies
  • Quality control (QC) analysis
  • QC release

Quality assurance for contract manufacturing and packing of pharmaceutical powders and liquids

A quality assurance (QA) system has been established to regulate all quality-related systems, methods and procedures.

All GMP topics are implemented by way of standards of practice (SOP). A GMP certificate (FAGG), a related production licence, and site master files are available.

QA is responsible for the coordination of the quality system. The qualified person is responsible for the release of the finished products.

Innovations in API Solubility and Bioavailability

API solubility and bioavailability, new technology for pharmaceutical products, twin screw technology, melt granulation and kneading and conveying, etc ... are all topics that are covered in this white paper.

A New Perspective on Joints

EKICART® is a patented nutraceutical for maintaining healthy joints and to support flexible movement.

Laboratoria Smeets NV

Fotografielaan 42

B-2610 Antwerpen-Wilrijk