ALG-009 is a small molecule commercialized by Aligos Therapeutics, with a leading Phase II program in Metabolic Dysfunction-Associated Steatohepatitis (MASH). According to Globaldata, it is involved in 3 clinical trials, of which 1 was completed, and 2 are ongoing. GlobalData uses proprietary data and analytics to provide a complete picture of ALG-009s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for ALG-009 is expected to reach an annual total of $18 mn by 2037 globally based off GlobalDatas Expiry Model. The drugs revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drugs phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
ALG-009 Overview
ALG-055009 is under development for the treatment of non-alcoholic steatohepatitis (NASH) and liver fibrosis. The drug candidate act by targeting thyroid hormone receptor beta (THR-beta). It is administered orally.
Aligos Therapeutics Overview
Aligos Therapeutics (Aligos) is a clinical-stage biopharmaceutical company developments therapeutics for liver and viral diseases. The company pipeline products include ALG-055009, a small molecule thyroid hormone receptor beta (THR-ß) agonist for metabolic dysfunction-associated steatohepatitis (MASH), and ALG-000184, a small molecule capsid assembly modulator for chronic hepatitis b (CHB). Aligo’s other pipeline products include ALG-097558 and ALG-125755. The company collaborates with various research institutes and biotech companies for drug development. It operates its offices in Belgium, the US and China. Aligos in headquartered in South San Francisco, California, the US.
The company reported revenues of (US Dollars) US$15.5 million for the fiscal year ended December 2023 (FY2023), an increase of 11.7% over FY2022. The operating loss of the company was US$88.1 million in FY2023, compared to an operating loss of US$97.6 million in FY2022. The net loss of the company was US$87.7 million in FY2023, compared to a net loss of US$96.1 million in FY2022.
The company reported revenues of US$1 million for the first quarter ended March 2024, a decrease of 63.2% over the previous quarter.
For a complete picture of ALG-009s valuation, buy the drugs risk-adjusted NPV model (rNPV) here.
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