ATH-1105 is under clinical development by Athira Pharma and currently in Phase I for Amyotrophic Lateral Sclerosis. According to GlobalData, Phase I drugs for Amyotrophic Lateral Sclerosis have an 87% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how ATH-1105’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

ATH-1105 overview

ATH-1105 is under development for the treatment of amyotrophic lateral sclerosis and frontotemporal dementia. The therapeutic candidate acts by targeting hepatocyte growth factor (HGF) and is administered through oral route in the form of solution.

Athira Pharma overview

Athira Pharma is a biopharmaceutical company that develops small molecules to treat neurodegenerative diseases and restore neuronal health. Its pipeline candidates include ATH-1020 treats neurodegenerative diseases, ATH-1105 treats amyotrophic lateral sclerosis; Fosgonimeton treats Parkinson’s disease, dementia and dementia with lewy bodies and early compounds treats neurodegenerative diseases. The company works in partnership with contract development and manufacturing organizations to manufacture and supply preclinical and clinical materials for the development of product candidates. Athira Pharma is headquartered in Bothell, Washington, the US.

For a complete picture of ATH-1105’s drug-specific PTSR and LoA scores, buy the report here.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.