Cassava Sciences. has been granted a patent for the preparation and properties of crystalline and amorphous polymorphs of a specific compound, along with its hydrochloride salts. The patent also covers a pharmaceutical composition containing these polymorphs and methods for their use. GlobalData’s report on Cassava Sciences gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Cassava Sciences, Molecular diagnosis biomarkers was a key innovation area identified from patents. Cassava Sciences's grant share as of July 2024 was 39%. Grant share is based on the ratio of number of grants to total number of patents.
Pharmaceutical composition of crystalline and amorphous compounds
The granted patent US12065440B2 outlines several claims related to pharmaceutical compositions that incorporate specific solid-state forms of compounds. The first claim describes a composition that includes a therapeutically effective amount of either a crystalline or amorphous compound, which is dispersed in a solid physiologically tolerable carrier or diluent. This compound is identified as a solid-state form of a compound represented by Formula III. The emphasis on both crystalline and amorphous forms suggests a focus on the versatility and potential stability of the pharmaceutical formulation.
Subsequent claims further detail similar compositions, specifically highlighting the use of crystalline compounds. Claim 2 specifies a composition containing a crystalline compound derived from a solid-state form of a compound represented by Formula II, while Claim 3 reiterates this structure for a compound of Formula I. Each claim underscores the importance of the solid-state form of the compounds in achieving therapeutic efficacy, as well as the role of the carrier or diluent in ensuring the composition's physiological tolerability. Overall, the patent presents a structured approach to developing pharmaceutical formulations that leverage specific solid-state forms of compounds for therapeutic applications.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
