The Diacylglycerol O Acyltransferase 1 pipeline drugs market research report outlays comprehensive information on the Diacylglycerol O Acyltransferase 1 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Diacylglycerol O Acyltransferase 1 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Gastrointestinal, Metabolic Disorders, and Dermatology which include the indications Metabolic Dysfunction-Associated Steatohepatitis (MASH), Dyslipidemia, Obesity, and Acne Vulgaris. It also reviews key players involved in Diacylglycerol O Acyltransferase 1 targeted therapeutics development with respective active and dormant or discontinued products.
The Diacylglycerol O Acyltransferase 1 pipeline targets constitutes close to five molecules. Out of which, approximately four molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Phase II, Phase I, and Preclinical stages are 1, 1, and 2 respectively. Similarly, the universities portfolio in Preclinical comprises 1 molecule.
Diacylglycerol O Acyltransferase 1 overview
Diglyceride acyltransferase 1 (DGAT-1) is an enzyme that catalyzes the formation of triglycerides from diacylglycerol and Acyl-CoA. It plays a role in esterifying exogenous fatty acids to glycerol. It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
For a complete picture of Diacylglycerol O Acyltransferase 1’s drug pipeline, buy the report here.
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