Epeleuton is under clinical development by Afimmune Biopharma and currently in Phase I for Sickle Cell Disease. According to GlobalData, Phase I drugs for Sickle Cell Disease have an 80% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Epeleuton’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.
GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.
Epeleuton overview
Epeleuton (AF-102) is under development for the treatment of non alcoholic fatty liver disease (NAFLD), idiopathic pulmonary fibrosis, alcoholic hepatitis, non-alcoholic steatohepatitis (NASH), type-2 diabetes, rare blood disorders, sickle cell disease, cardiovascular risk reduction, chronic obstructive pulmonary disease (COPD), Coronavirus disease 2019 (COVID-19) and atherosclerosis. It is a bioactive lipid administered orally as a capsule. It was under development for idiopathic pulmonary fibrosis, type-2 diabetes, hypertriglyceridemia
Afimmune Biopharma overview
AFIMMUNE Biopharma is a drug discovery and development company working on inflammatory conditions of the primary organs including the heart and the liver. AFIMMUNE Biopharma is headquartered in Leopardstown, Dublin, Ireland.
For a complete picture of Epeleuton’s drug-specific PTSR and LoA scores, buy the report here.
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