Gene Therapy to Target MS4A1 for Chronic Lymphocytic Leukemia, Refractory and Relapsed Diffuse Large B-cell Lymphoma is under clinical development by AbelZeta and currently in Phase I for Non-Hodgkin Lymphoma. According to GlobalData, Phase I drugs for Non-Hodgkin Lymphoma have a 72% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how Gene Therapy to Target MS4A1 for Chronic Lymphocytic Leukemia, Refractory and Relapsed Diffuse Large B-cell Lymphoma’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

Gene Therapy to Target MS4A1 for Chronic Lymphocytic Leukemia, Refractory and Relapsed Diffuse Large B-cell Lymphoma overview

Gene therapy is under development for the treatment of chronic lymphocytic leukemia(CLL), refractory and relapsed diffuse large B-cell lymphoma resistant to anti-CD19 therapy. It comprises T-cells modified by using lentivirus to express chimeric antigen receptors(CAR) targeting CD20.

AbelZeta overview

AbelZeta, formerly Cellular Biomedicine Group Inc, is a clinical-stage biopharmaceutical firm that develops biomedicine, and immunotherapy products for cancer and stem cell therapies to address patient-specific medical conditions. The firm’s products comprise clinical treatment protocols for the treatment of knee osteoarthritis, cancer, asthma and chronic obstructive pulmonary diseases. It offers treatment protocol services such as orthopedic diseases including osteoarthritis and tissue damage; and other indications. AbelZeta utilizes proprietary cell-based technologies to produce raw materials, manufacture cells, and conduct cell banking and distribution. The firm has operations in Hong Kong, China and the US. AbelZeta is headquartered in Cupertino, California, the US.

For a complete picture of Gene Therapy to Target MS4A1 for Chronic Lymphocytic Leukemia, Refractory and Relapsed Diffuse Large B-cell Lymphoma’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 18 March 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.