Kodiak Sciences. has filed a patent for random copolymers that include zwitterions and functional agents. The patent also covers the methods of preparing these copolymers. GlobalData’s report on Kodiak Sciences gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Kodiak Sciences, Nanoparticle drug conjugates was a key innovation area identified from patents. Kodiak Sciences's grant share as of September 2023 was 31%. Grant share is based on the ratio of number of grants to total number of patents.
Random copolymers containing zwitterions and functional agents
A recently filed patent (Publication Number: US20230277616A9) describes a random copolymer that consists of two monomers distributed randomly throughout the polymer. The first monomer contains a phosphorylcholine, while the second monomer is linked to a functional agent. The patent also includes claims for variations of the random copolymer, such as those with multiple polymer arms and different types of initiator fragments.
The random copolymer can have various applications due to the inclusion of functional agents. These functional agents can be bioactive agents, detection agents, imaging agents, labeling agents, or diagnostic agents. Examples of bioactive agents include therapeutic proteins, antibodies or antibody fragments, and drugs.
The patent also provides details on the composition of the random copolymer. It can consist of different ratios of first and second monomers, ranging from 100:1 to 1:100. The weight average molecular weight of the copolymer can range from about 1000 to 1,500,000 Daltons, and it has a polydispersity of less than 1.5.
The patent further describes methods for making the random copolymer. It involves contacting a mixture of the first and second monomers with an initiator under conditions that allow for free radical polymerization. This process results in the formation of the random copolymer, with the first monomer containing a phosphorylcholine and the second monomer linked to a functional agent.
Overall, this patent presents a novel random copolymer with potential applications in various fields, including medicine and diagnostics. The inclusion of functional agents and the ability to vary the composition of the copolymer make it a versatile material for different purposes. The detailed claims and methods provided in the patent offer valuable insights into the composition and production of this random copolymer.
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