LTI-01 is under clinical development by Aileron Therapeutics and currently in Phase II for Empyema. According to GlobalData, Phase II drugs for Empyema does not have sufficient historical data to build an indication benchmark PTSR for Phase II. GlobalData uses proprietary data and analytics to create drugs-specific PTSR and LoA in the LTI-01 LoA Report. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

LTI-01 overview

LTI-01 is under development for the treatment of loculated pleural effusions and empyema. It is administered through intrapleural route. It is a proenzyme or zymogen and becomes activated in the pleural space. The therapeutic candidate is a new molecular entity.

Aileron Therapeutics overview

Aileron Therapeutics is a biopharmaceutical company. The company develops medicines to make chemotherapy safer and thereby more effective to save more patients’ lives. Its products include ALRN-6924 MDM2 and MDMX dual inhibitor a chemoprotective agent that treats patients with p53-mutated cancers. It also provides radioprotection, anti-cancer research and discovery research. The company partners with research organizations to provide its products. Aileron Therapeutics is headquartered in Boston, Massachusetts, the US.

For a complete picture of LTI-01’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 18 April 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.