Masofaniten is a small molecule commercialized by ESSA Pharma, with a leading Phase I program in Castration-Resistant Prostate Cancer (CRPC). According to Globaldata, it is involved in 8 clinical trials, of which 3 are ongoing, 4 are planned, and 1 was terminated. GlobalData uses proprietary data and analytics to provide a complete picture of Masofaniten’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
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The revenue for Masofaniten is expected to reach an annual total of $57 mn by 2035 globally based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Masofaniten Overview
ESSA Pharma Overview
ESSA Pharma is a drug developer that offers oncology therapeutics. The company’s pipeline products include EPI-506 in which it includes the programs 3rd-Generation AR N-terminal domain inhibitor, AR N-terminal domain, tau-1 site inhibitor, AR N-terminal, domain degrader among others. It offers clinical trials. The company has collaboration with the cancer prevention and research institute to advance science for cancer biology developments. It operates in Canada and the US. ESSA Pharma is headquartered in Vancouver, British Columbia, Canada.
The operating loss of the company was US$32.1 million in FY2023, compared to an operating loss of US$37 million in FY2022. The net loss of the company was US$26.6 million in FY2023, compared to a net loss of US$35.1 million in FY2022.
For a complete picture of Masofaniten’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.
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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.
To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.
The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.
