MB-CART 19.1 is under clinical development by Miltenyi Biomedicine and currently in Phase II for Acute Lymphocytic Leukemia (ALL, Acute Lymphoblastic Leukemia). According to GlobalData, Phase II drugs for Acute Lymphocytic Leukemia (ALL, Acute Lymphoblastic Leukemia) have a 36% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how MB-CART 19.1’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

MB-CART 19.1 overview

MB-CART 19.1 is under development for the treatment of relapsed and refractory acute lymphocytic leukemia, B-cell non-Hodgkin lymphoma chronic lymphocytic leukemia and systemic lupus erythematosus. It is administered through the intravenous route. The therapeutic candidate consists of T cells engineered to express chimeric antigen receptors (CAR T-cells). It acts by targeting cells expressing CD19 antigen and being developed based on Mono CART technology. It was also under development for the treatment of acute lymphoblastic lymphoma.

Miltenyi Biomedicine overview

Miltenyi Biomedicine, a subsidiary of Miltenyi Biotec GmbH, is a biopharmaceutical company that develops innovative cell and gene therapies and regenerative therapies for cancer treatments.

For a complete picture of MB-CART 19.1’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 16 July 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.