Sasanlimab is a monoclonal antibody commercialized by Pfizer, with a leading Phase III program in Non Muscle Invasive Bladder Cancer (NMIBC) (Superficial Bladder Cancer). According to Globaldata, it is involved in 12 clinical trials, of which 1 was completed, 8 are ongoing, 1 is planned, and 2 were terminated. GlobalData uses proprietary data and analytics to provide a complete picture of Sasanlimab’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
The revenue for Sasanlimab is expected to reach an annual total of $34 mn by 2035 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Sasanlimab (PF-06801591) is under development for the treatment of non muscle invasive bladder cancer, sarcoma, metastatic melanoma, muscle invasive bladder cancer, head and neck cancer squamous cell carcinoma, non-small cell lung cancer, urothelial carcinoma, ovarian cancer and other solid tumors. The drug candidate is administered intravenously and subcutaneously. The drug candidate is a monoclonal antibody which targets programmed cell death protein1 (PD-1). The drug candidate is a new molecular entity.
Pfizer discovers, develops, manufactures, and commercializes biopharmaceuticals. The company offers products to treat various conditions such as cardiovascular, metabolic and pain, women’s health, cancer, inflammation, immune disorders, and rare diseases. It also provides sterile injectable pharmaceuticals, biosimilars, active pharmaceutical ingredients (APIs) and contract manufacturing services. Pfizer sells its products through wholesalers, retailers, hospitals, individual provider offices, clinics, government agencies and pharmacies. It has major manufacturing facilities in India, China, Japan, Ireland, Italy, Belgium, Germany, Singapore, and the US. The company provides its products in North America, South America, Asia-Pacific, Australia, Europe, Africa, and the Middle East. Pfizer is headquartered in New York, the US.
The company reported revenues of (US Dollars) US$100,330 million for the fiscal year ended December 2022 (FY2022), an increase of 23.4% over FY2021. In FY2022, the company’s operating margin was 36.4%, compared to an operating margin of 29.1% in FY2021. In FY2022, the company recorded a net margin of 31.3%, compared to a net margin of 27% in FY2021. The company reported revenues of US$18,282 million for the second quarter ended April 2023, a decrease of 24.7% over the previous quarter.
For a complete picture of Sasanlimab’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.