Shattuck Labs has been granted a patent for a chimeric protein structure involving FLT3L and 4-1 BBL extracellular domains for disease treatment, particularly cancer. The invention focuses on compositions and methods utilizing this protein structure. GlobalData’s report on Shattuck Labs gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on Shattuck Labs, Peptide pharmacophores was a key innovation area identified from patents. Shattuck Labs's grant share as of February 2024 was 10%. Grant share is based on the ratio of number of grants to total number of patents.
Chimeric protein for cancer treatment
A recently granted patent (Publication Number: US11896618B2) discloses a chimeric protein structure with a specific composition. The protein consists of three main components: a first domain containing the extracellular domain of FMS like tyrosine kinase 3 ligand (FLT3L), a linker connecting the first domain to a second domain, and the second domain comprising the extracellular domain of 4-1 BB ligand (4-1 BBL). This unique structure is designed for potential applications in various fields, leveraging the properties of the FLT3L and 4-1 BBL domains.
Moreover, the patent also includes variations of the chimeric protein, such as those with a linker incorporating a Fc domain derived from IgG1 or IgG4. Additionally, the linker may further include one or more joining linkers selected from specific sequences (SEQ ID NOs: 4-50). These variations aim to enhance the functionality and versatility of the chimeric protein, potentially expanding its utility in different contexts. Overall, the patent provides a detailed description of the chimeric protein and its variants, offering insights into the innovative design and potential applications of these structures in various fields of research and development.
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GlobalData Patent Analytics tracks bibliographic data, legal events data, point in time patent ownerships, and backward and forward citations from global patenting offices. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies
