The Signal Transducer And Activator Of Transcription 5 pipeline drugs market research report outlays comprehensive information on the Signal Transducer And Activator Of Transcription 5 targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA), and molecule type. GlobalData’s report assesses the drugs in the Signal Transducer And Activator Of Transcription 5 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline. Buy the report here.
The report also covers products from therapy areas such as Oncology, and Toxicology which include the indications Leukemia, Chronic Myelocytic Leukemia (CML, Chronic Myeloid Leukemia), and Chemotherapy Induced Neutropenia. It also reviews key players involved in Signal Transducer And Activator Of Transcription 5 targeted therapeutics development with respective active and dormant or discontinued products.
The Signal Transducer And Activator Of Transcription 5 pipeline targets constitutes close to six molecules. Out of which, approximately four molecules are developed by companies and the remaining by the universities/institutes. The molecules developed by companies in Preclinical, and Discovery stages are 3, and 1 respectively. Similarly, the universities portfolio in Discovery comprises 2 molecule.
Signal Transducer And Activator Of Transcription 5 overview
Signal transducer and activator of transcription 5A (STAT5) protein encoded by this gene STAT5A is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis.
For a complete picture of Signal Transducer And Activator Of Transcription 5’s drug pipeline, buy the report here.
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