Tinlarebant is a small molecule commercialized by Belite Bio, with a leading Phase III program in Juvenile Macular Degeneration (Stargardt Disease). According to Globaldata, it is involved in 9 clinical trials, of which 4 were completed, and 5 are ongoing. GlobalData uses proprietary data and analytics to provide a complete picture of Tinlarebant’s valuation in its risk-adjusted NPV model (rNPV). Buy the model here.
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The revenue for Tinlarebant is expected to reach an annual total of $164 mn by 2036 in the US based off GlobalData’s Expiry Model. The drug’s revenue forecasts along with estimated costs are used to measure the value of an investment opportunity in that drug, otherwise known as net present value (NPV). Applying the drug’s phase transition success rate to remaining R&D costs and likelihood of approval (LoA) to sales related costs provides a risk-adjusted NPV model (rNPV). The rNPV model is a more conservative valuation measure that accounts for the risk of a drug in clinical development failing to progress.
Tinlarebant Overview
LBS-008 is under development for the treatment of geographic atrophy (GA) associated with dry AMD. and stargardt macular dystrophy (juvenile onset of macular degeneration). The drug candidate is administered through the oral route. The drug candidate acts by targeting retinol binding protein 4 (RBP4).
Belite Bio Overview
Belite Bio is a clinical-stage biopharmaceutical drug development business focused on innovative treatments for untreatable retinal degeneration illnesses such as atrophic age-related macular degeneration and STGD1. The company is headquartered in United States.
The operating loss of the company was US$12.8 million in FY2022, compared to an operating loss of US$9.8 million in FY2021. The net loss of the company was US$12.7 million in FY2022, compared to a net loss of US$9.7 million in FY2021.
For a complete picture of Tinlarebant’s valuation, buy the drug’s risk-adjusted NPV model (rNPV) here.
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To create this model, GlobalData takes into account factors including patent law, known and projected regulatory approval processes, cash flows, drug margins and company expenses. Combining these data points with GlobalData’s world class analysis creates high value models that companies can use to help in evaluation processes for each drug or company.
The rNPV method integrates the probability of a drug reaching a clinical stage into the cash flow at that time, which provides a more accurate valuation, as it considers the probability that the drug never makes it through the clinical pathway to commercialization. GlobalData’s rNPV model uses proprietary likelihood of approval (LoA) and phase transition success rate (PTSR) data for the indication in the highest development stage, which can be found on GlobalData’s Pharmaceutical Intelligence Center.
