TNX-1500 is under clinical development by Tonix Pharmaceuticals Holding and currently in Phase I for Kidney Transplant Rejection. According to GlobalData, Phase I drugs for Kidney Transplant Rejection have a 92% phase transition success rate (PTSR) indication benchmark for progressing into Phase II. GlobalData’s report assesses how TNX-1500’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

TNX-1500 overview

TNX-1500 is under development for the prevention and treatment of organ transplant rejection and for treatment of autoimmune disorders including systemic lupus erythematosus, sjogren’s syndrome, rheumatoid arthritis, multiple sclerosis and allergy. It acts by targeting CD40 ligand (CD154). It is a new molecular entity (NME). The drug candidate is administered through intravenous route.

Tonix Pharmaceuticals Holding overview

Tonix Pharmaceuticals Holding (Tonix) a developer of pharmaceutical products to address public health challenges. The company offers pharmaceutical products and treatments for disorders of the central nervous system including fibromyalgia, post-traumatic stress disorder and episodic tension-type headache. Its products include Central Nervous System Portfolio; TNX-102 SL, TNX-1300, TNX-1900, Immunology Portfolio; TNX-1500(Organ Transplant Rejection / Autoimmune Disorders), TNX-1850 COVID-19 Vaccine and Rare Disease Portfolio; TNX-2900 (Prader-Willi Syndrome). Its disintegrating sublingual tablets contain a dose and formulation of cyclobenzaprine and are used for the treatment of fibromyalgia and post-traumatic stress disorder. It markets its products through a network of distributors across the US. It has operations in Ireland, Canada and the US. Tonix is headquartered in New York, the US

For a complete picture of TNX-1500’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.