TW-012R is under clinical development by Time Therapeutics and currently in Phase II for Alzheimer’s Disease. According to GlobalData, Phase II drugs for Alzheimer’s Disease have a 36% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how TW-012R’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

TW-012R overview

Bromocriptine (TW-012R) is under development for the treatment of  familial Alzheimer’s disease bearing PSEN1 (presenilin 1) mutations (PSEN1-AD). It is administered through oral route as tablets. The drug candidate is a repurposed drug of bromocriptine mesylate and acts by targeting dopamine D2 receptor.

Time Therapeutics overview

Time Therapeutics is a company that provides society with treatment for diseases that have no fundamental cure. The company is Headquartered in Japan.

For a complete picture of TW-012R’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.