UWC-19 is under clinical development by UWELL Biopharma and currently in Phase II for Burkitt Lymphoma. According to GlobalData, Phase II drugs for Burkitt Lymphoma have a 40% phase transition success rate (PTSR) indication benchmark for progressing into Phase III. GlobalData’s report assesses how UWC-19’s drug-specific PTSR and Likelihood of Approval (LoA) scores compare to the indication benchmarks. Buy the report here.

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GlobalData tracks drug-specific phase transition and likelihood of approval scores, in addition to indication benchmarks based off 18 years of historical drug development data. Attributes of the drug, company and its clinical trials play a fundamental role in drug-specific PTSR and likelihood of approval.

UWC-19 overview

UWC-19 is under development for the treatment of advanced relapsed or refractory CD19 positive hematologic malignancies including acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), B cell non-Hodgkin lymphoma including primary mediastinal large B cell lymphoma (PMBCL), transformation follicular lymphoma (TFL), high grade B-cell lymphoma (HGBCL), mantle cell lymphoma (MANT), burkitt lymphoma (BURK), lymphoblastic lymphoma. The drug candidate is administered through parenteral and intravenous routes. The therapeutic candidate comprises of autologous T lymphocytes genetically-modified to express CD19-targeting chimeric antigen receptor.

For a complete picture of UWC-19’s drug-specific PTSR and LoA scores, buy the report here.

This content was updated on 10 June 2024

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Likelihood of Approval analytics tool dynamically assesses and predicts how likely a drug will move to the next stage in clinical development (PTSR), as well as how likely the drug will be approved (LoA). This is based on a combination of machine learning and a proprietary algorithm to process data points from various databases found on GlobalData’s Pharmaceutical Intelligence Center.